Z2 Auto Ultra Portable Auto-CPAP Machine Package


14 Total Reviews

Z2 Auto Ultra Portable Auto-CPAP Machine Package
A prescription is required for the purchase of this item
2-Year Manufacturer's Warranty + Free 15-Night Money Back Guarantee
Battery Options:
No Thanks, I Don't Need a Battery
Integrated PowerShell with Extended Life Battery
Pilot-12 Lite Battery Pack
No Thanks, I Don't Need a Travel Bag
Premium Soft Drawstring Travel Bag
4-Foot SlimStyle Tube
4-Foot SlimStyle Tube + 6-Foot SlimStyle Tubing
1 Air Filter Pre-Installed + 1 Replacement Filter
1 Air Filter Pre-Installed + 3 Replacement Filters
Universal AC Power Supply with Cord
1 HME Humidifier Filter (for Optional Use)
5 HME Humidifier Filters (for Optional Use)
Data Cable:
Micro USB Cable
Was $899.00  $799.00

  • Brand:Human Design Medical
  • Warranty:Exclusive 15-Night Money Back Guarantee & 2-Year Manufacturer's Warranty

With a new, quieter motor the Z2 Auto is one of the smallest, lightest, most portable Auto-CPAPs in the world. It provides responsive, customized sleep therapy, adjusting pressures automatically to ensure you receive the lowest, most comfortable, levels possible for successful sleep therapy. Z2 Auto includes a 30-Night Money Back Guarantee and a 2-Year Extended Warranty so you can rest assured knowing it is built from the ground up with quality in mind.


  • Lightweight for Travel, Great for Home Too!
  • Auto-Adjusting Sleep Therapy
  • Z-Breathe Pressure Relief
  • Whisper Quiet
  • Auto Start & Stop Ease of Use
  • Auto Altitude Adjusting
  • Optional PowerShell Integrated Battery
  • Automatic Leak Compensation
  • Ramp for Comfort
  • Big, Bright, Intelligent LCD Display
  • Humidification Options
  • Nitelog: Free iOS & Android App
  • Compatible with any CPAP Mask

Lightweight for Travel, Great for Home Too!:The Z2 Auto CPAP builds on the form of the original Z1 with a more advanced, quieter motor and improved software systems. The Z2 Auto is tiny so it fits easily in your hand; and ultra-light at just 10.4 ounces. It is a great everyday machine that is also ideal for travel, packing easily in carry on luggage or any travel bag.

Auto-Adjusting Sleep Therapy: With its proprietary breathing algorithm, and sampling rate of several times per second, the Z2 Auto delivers therapy at a lower overall average pressure than a fixed-pressure CPAP so it's more comfortable, more successful, and easier to use.

Z-Breathe Pressure Relief: Z2 Auto delivers a more natural breathing experience with a proprietary feature, called Z-Breathe, that smooths therapy pressure -- reducing spikes in pressure during exhalation and drops in pressure during inhalation -- to deliver more comfortable therapy. Z-Breathe has 3 settings so you can set it to suit your own personal needs.

Whisper Quiet: The Z2 Auto has a new quieter motor built for sleep so it is very quiet. In fact it's one of the quietest APAPs on the market, producing only 26 dBA on average of sound during operation.

Auto Start & Stop Ease of Use: The Z2 Auto comes with an Auto Start / Stop Feature. Simply place your CPAP mask on your face and therapy will start when the device senses you've started to breathe. The Z2 will then stop delivering therapy within seconds of the mask being removed from the face or when a large leak is detected. It's as simple as that!

Auto Altitude Adjusting: The Z2 Auto automatically adjusts to altitudes up to 8,000 feet above sea level; and complies with FAA for use on airplanes. When traveling outside the US the Z2 Auto will convert the voltage automatically so you can continue enjoying safe and comfortable sleep therapy wherever your next adventure takes you. (Plug adapter may be needed outside of North America).

Optional PowerShell Integrated Battery: For nights away from fixed power the optional PowerShell with Extended Life Battery Pack provides an innovative, integrated solution, merging the machine and battery in one convenient package. The PowerShell holds one battery that will last 1-2 nights between charges; and batteries recharge using the Z2's standard power supply so there are no extra cords to worry about. For extra nights away just add additional batteries! The PowerShell can also be used as a backup power supply, automatically taking over during a power outage or blackout.

Automatic Leak Compensation: To ensure you're always receiving your prescribed sleep therapy pressure the Z2 Auto automatically compensates for minor mask leaks. If Z2 detects an excessive air leak, that could be detrimental to therapy, its display screen will warn you to ensure that the leak is corrected promptly.

Ramp for Comfort: For people who prefer to fall asleep with therapy at lower pressure levels, the Z2's ramp feature allows you to start your pressure at a lower setting and ramp it up over time to let you adjust more gradually to sleep therapy.

Big, Bright, Intelligent LCD Display: The Z2's large, backlit LCD display provides information on your current pressure setting, ramp time, power status, and more. With the Z2 you can always check your current therapy status, but don't worry the display has an auto-off function so it won't disturb you as you drift off to sleep.

Humidification Options: If you prefer added humidification when using sleep therapy, the Z2 comes complete with an inline HME Waterless Humidification Filter. A unique alternative to bulky water based humidifiers, HME Filters capture heat and moisture from your breathing as you exhale, preserving and increasing humidity to prevent your airways from drying out during therapy.

Nitelog: Free iOS & Android App: Do you need to track your sleep therapy progress for your job, your doctor or just for your own peace of mind? Download the Nitelog App from the iTunes or Android Store and have all the sleep data from you Z2 available at your fingertips. Nitelog uses the Z2 Auto's built-in Bluetooth chip to sync data wirelessly so it is simple to set up and use. It also enables sharing by email so you can send data to your doctor whenever you need to.

Compatible with any CPAP Mask: The Z2 comes with a Universal Tube Adapter and a 48 inch slim tube. If you prefer longer tubing or performance tubing it can be used with that too; and Z2 will work with any CPAP mask on the market so choose your favorite... don't worry it IS compatible!


  • Manufacturer:Human Design Medical
  • Part Numbers:718116
  • Warranty:Exclusive 15-Night Money Back Guarantee & 2-Year Manufacturer's Warranty
  • In The Package:Z2 Auto CPAP Machine, 4-Foot SlimStyle Tubing, 2 Air Filters, Universal Tube Adapter, Universal AC Power Supply with Cord, Micro USB Cable, Printed Instructions, Heat Moisture Exchange (HME) Humidifier Filter, QTube Inline Muffler (for Optional Use), and 2 Year Manufacturer's Warranty. Additional custom options available in shopping cart.
  • HCPCS Codes:E1399
  • GTIN Codes:00859477004284
  • RX Required:Prescription required prior to shipment. Click to learn more about submitting prescriptions.
  • FLEX SPENDING:Can be purchased with FSA & HSA Cards


Z2 Auto is FAA Approved. This product is approved by the FAA for use on all commercial flights within the US; and all international flights that depart or arrive in the US. Always contact your airline prior to your flight to confirm any requirements they may have -- such as a copy of your prescription or a letter of medical necessity -- for allowing your device on board.


  • Dimensions:6.48 x 3.30 x 2.02 Inches
  • Weight:10.5 Ounces
  • Materials:Latex Free


  • Dimensions:6.48 x 3.30 x 2.02 Inches
  • Weight:10.4 Ounces
  • Operating Modes:CPAP, Auto-CPAP (APAP)
  • Pressure Range:4 to 20 cm H2O
  • Tubing Compatibility:The Z2 includes a Custom Tube Adapter compatible with all Standard and Performance CPAP Tubing. For proper operation the Tube Adapter MUST ALWAYS be in place when using the Z2 device.
  • Sound Levels:26 dBA
  • Default Settings: 4-10 CM H2O, Ramp 15 Minutes, Ramp Start Pressure 4.0, Z-Breathe APAP-3, BlueTooth On


  • Comfort Tech:Z-Breathe (Settings = 1 Minimum, 2 Moderate, 3 Maximum)
  • Leak Compensation:Automatic
  • Pressure Ramp:User Adjustable 0 to 45 Minutes
  • Pressure Ramp Start: 4 to Minimum Pressure
  • Altitude Adjustment: Automatic Up To 8000 Feet
  • Auto Start & Stop: The Z2 Auto comes with an Auto Start / Stop Feature
  • Supplemental Oxygen: NOT Compatible with Supplemental Oxygen


  • Data Storage: 30 Days of Storage Onboard
  • Data Viewing:Free NiteLog App (iOS or Android)
  • Data Included: Events and Time of Use


  • Humidifier:Heat Moisture Exchanger (HME) Included for Optional Use


  • AC Power: AC Power Supply with Cord
  • AC Input Range:Univeral 100-240 VAC, 50/60 Hz, 2.0-1.0 A
  • AC Power Supply Dimensions:3.75 x 1.75 x 1.25 Inches
  • AC Cord Weight:9.5 Ounces
  • AC Cord Length:10 Feet 4 Inches
  • AC Consumption:Typical 20 Watts (30VA); Peak 35 Watts (70VA)


  • DC Power:Optional Accessory
  • DC Cord Weight:3 Ounces
  • DC Cord Length:6 Feet 6 Inches
  • DC Cord Fuses:5 Amp
  • DC Consumption:12 Volts or 24 Volts


  • Battery Dimensions:PowerShell = 6.00 x 4.25 x 3.00 Inches Extended Life Battery = 6.13 x 4.00 x 1.38 Inches
  • Battery Weight:PowerShell = 9.8 Ounces Extended Life Battery Module = 15.5 Ounces
  • Battery Runtime:1-2 Nights Per Extended Life Battery Depending on Settings. Lower pressure settings will increase run times and higher pressure settings will decrease run times. At a pressure setting of 20CM most users will achieve more than 8 hours of run time per battery.
  • Battery Recharge Time:Up to 8 Hours
  • Battery Life:300 Cycles
  • Battery Capacity:99 Watt Hours
  • Battery Notes:For best performance Battery Modules should be fully charged prior to first use. Batteries recharge in the PowerShell when connected to AC or DC Power. In-house tests at DirectHomeMedical show that using a 4-foot tube and low Z-Breathe settings can increase overall battery run times. For complete care and use instructions, refer to the manual that came with your sleep therapy device or PowerShell.
  • Excellent!


    Thanks to the excellent service I received from cpapXchange.com team. My CPAP machine works perfectly. Its amazingly comfortable and wonderful to sleep through the night without interruptions.
    Written by ,

  • Works Better than Expected


    The Breas Z2 travel CPAP is fantastic and easy to use. It works better than the advertisement states. The only difficulty I have is that it shuts off if your mask has a leak.
    Written by , Delaware

  • Great price


    Great price, fast response and updates. Will buy from cpapXchange again.
    Written by , MI

  • Small, light and powerful


    Love this CPAP. I am heading out on a trip soon and this CPAP is a perfect travel options. It is so small and absolutely one of, if not the, smallest on the market. It's pretty quiet, although not as quiet as the ratings. Although the ratings claim 26 dB, it actually functions at closer to 39 dB. Nonetheless, it's not too bothersome and I'm a pretty light sleeper. The smart phone app works perfectly and overall I am very pleased with this CPAP comparing it to my AirSense 11 home CPAP. Highly recommended!
    Written by , New Hampshire

  • The machine


    1st off you cant use one of the mask cleaning machines you meed to wash your mask everyday. I dont remember reading that part when I did my research. I like the small size and having the battery. I had problems with settings and seemed to get those fixed but I decided to chang masks and now having setting issues again
    Written by , Online

  • Good service


    Quick response andd shipping.
    Written by ,

  • Good only if you are deaf


    Unless your partner is deaf and you can sleep with a small jet engine in the room - do not buy. Very loud.
    Written by , reading pa

  • Great portable unit.


    Have not used it for travel yet.
    Written by , AK

  • Great traveling CPAP


    Been using this machine for a few days and it’s been great. It’s quiet, lightweight, easy to use and set up!
    Written by , Atlanta

  • great CPAP machine


    I am pleased with this cpap machine.
    Written by ,

  • Love the Z2


    I’ve had the Z1 for quite a while & it finally quit. I ordered the Z2 & it’s even better. Quieter, auto on & off & uses all the same supplies & accessories. Great experience shopping on line with quick delivery & no hassles.
    Written by , Gold Hill, OR

  • Excellent, small machine


    I have purchased several items from this company. The items are shipped quickly, the prices fair and the customer service outstanding. The Z2 Auto ultra portable Auto-CPAP machine is quiet, small and comfortable to use. I would recommend it.
    Written by , California

  • Not sure


    Not sure if settings match my prescription
    Written by ,

  • better than the z1


    i've had a z1 for a long time. it always looked great, but i wasn't particularly happy with the noise levels. i figured i could try the new one risk free so why not give it a shot. the new machine feels a lot better than the old one - more sturdy - and it definitely sounds quieter. there is still a noise so you know it's on but it's not much different than my home cpap. overall i'm very impressed. the manufacturer name on the unit has changed, so maybe they got bought out?
    Written by , Beantown