Z2 Ultra Portable CPAP Machine Package


4 Total Reviews

Z2 Portable CPAP Machine
2-Year Manufacturer's Warranty + Free 15-Night Money Back Guarantee
Battery Options:
No Thanks, I Don't Need a Battery
Integrated PowerShell with Extended Life Battery
Pilot-12 Lite Battery Pack
No Thanks, I Don't Need a Travel Bag
Premium Soft Drawstring Travel Bag
4-Foot SlimStyle Tube
4-Foot SlimStyle Tube + 6-Foot SlimStyle Tubing
1 Air Filter Pre-Installed + 1 Replacement Filter
1 Air Filter Pre-Installed + 3 Replacement Filters
Universal AC Power Supply with Cord
1 HME Humidifier Filter (for Optional Use)
5 HME Humidifier Filters (for Optional Use)
Data Cable:
Micro USB Cable
A prescription is required for the purchase of this item
Was $859.00  $799.00

  • Brand:Human Design Medical
  • Warranty:Exclusive 15-Night Money Back Guarantee & 2-Year Manufacturer's Warranty

With a new, quieter motor the Z2 is one of the smallest, lightest, most portable CPAPs in the world. Designed, engineered, and assembled in America, Z2 CPAP is as an advanced, fixed pressure sleep therapy device in a super small package you can pick up and take on the road. Z2 includes a 15-Night Money Back Guarantee and a 2-Year Extended Warranty so you can rest assured knowing it is built from the ground up with quality in mind.


  • Lightweight for Travel, Great for Home Too!
  • Fixed Pressure Therapy with a Ramp for Comfort
  • Z-Breathe Pressure Relief
  • Whisper Quiet
  • Auto Stop Ease of Use
  • Auto Altitude Adjusting
  • Optional PowerShell Integrated Battery
  • Automatic Leak Compensation
  • Ramp for Comfort
  • Big, Bright, Intelligent LCD Display
  • Humidification Options
  • Compatible with any CPAP Mask

Lightweight for Travel, Great for Home Too!:The Z2 CPAP builds on the form of the original Z1 with a more advanced, quieter motor and improved software systems. The Z2 is tiny so it fits easily in your hand; and ultra-light at just 10.4 ounces. It is a great everyday machine that is also ideal for travel, packing easily in carry on luggage or any travel bag.

Fixed Pressure Therapy with a Ramp for Comfort: The Z2 CPAP delivers fixed therapy CPAP pressure at prescribed settings between 4-20 CM. For people who prefer to fall asleep with therapy at lower pressure levels, the Z2's ramp feature allows you to start your pressure at a lower setting and ramp it up over time to let you adjust more gradually to sleep therapy.

Z-Breathe Pressure Relief: Z2 delivers a more natural breathing experience with a proprietary feature, called Z-Breathe, that smooths therapy pressure -- reducing spikes in pressure during exhalation and drops in pressure during inhalation -- to deliver more comfortable therapy. Z-Breathe has 3 settings so you can set it to suit your own personal needs.

Whisper Quiet: The Z2 has a new quieter motor built for sleep so it is very quiet. In fact it's one of the quietest APAPs on the market, producing only 26 dBA on average of sound during operation.

Auto Stop Ease of Use: The Z2 CPAP is programmed to stop delivering therapy within seconds of the mask being removed from the face or when a large leak is detected. No more fumbling to find the stop button in the dark.

Auto Altitude Adjusting: The Z2 CPAP automatically adjusts to altitudes up to 8,000 feet above sea level; and complies with FAA for use on airplanes. When traveling outside the US the Z2 will convert the voltage automatically so you can continue enjoying safe and comfortable sleep therapy wherever your next adventure takes you. (Plug adapter may be needed outside of North America).

Optional PowerShell Integrated Battery: For nights away from fixed power the optional PowerShell with Extended Life Battery Pack provides an innovative, integrated solution, merging the machine and battery in one convenient package. The PowerShell holds one battery that will last 1-2 nights between charges; and batteries recharge using the Z2's standard power supply so there are no extra cords to worry about. For extra nights away just add additional batteries! The PowerShell can also be used as a backup power supply, automatically taking over during a power outage or blackout.

Automatic Leak Compensation: To ensure you're always receiving your prescribed sleep therapy pressure the Z2 automatically compensates for minor mask leaks. If Z2 detects an excessive air leak, that could be detrimental to therapy, its display screen will warn you to ensure that the leak is corrected promptly.

Ramp for Comfort: For people who prefer to fall asleep with therapy at lower pressure levels, the Z2's ramp feature allows you to start your pressure at a lower setting and ramp it up over time to let you adjust more gradually to sleep therapy.

Big, Bright, Intelligent LCD Display: The Z2's large, backlit LCD display provides information on your current pressure setting, ramp time, power status, and more. With the Z2 you can always check your current therapy status, but don't worry the display has an auto-off function so it won't disturb you as you drift off to sleep.

Humidification Options: If you prefer added humidification when using sleep therapy, the Z2 comes complete with an inline HME Waterless Humidification Filter. A unique alternative to bulky water based humidifiers, HME Filters capture heat and moisture from your breathing as you exhale, preserving and increasing humidity to prevent your airways from drying out during therapy.

Compatible with any CPAP Mask: The Z2 comes with a Universal Tube Adapter and a 48 inch slim tube. If you prefer longer tubing or performance tubing it can be used with that too; and Z2 will work with any CPAP mask on the market so choose your favorite... don't worry it IS compatible!


  • Manufacturer:Human Design Medical
  • Part Numbers:717116
  • Warranty:Exclusive 15-Night Money Back Guarantee & 2-Year Manufacturer's Warranty
  • In The Package:Z2 CPAP Machine, 4-Foot SlimStyle Tubing, 2 Air Filters, Universal Tube Adapter, Universal AC Power Supply with Cord, Micro USB Cable, Printed Instructions, Heat Moisture Exchange (HME) Humidifier Filter, QTube Inline Muffler (for Optional Use), and 2 Year Manufacturer's Warranty. Additional custom options available in shopping cart.
  • HCPCS Codes:E1399
  • GTIN Codes:00859477004277
  • RX Required:Prescription required prior to shipment. Click to learn more about submitting prescriptions.
  • FLEX SPENDING:Can be purchased with FSA & HSA Cards


Z2 is FAA Approved. This product is approved by the FAA for use on all commercial flights within the US; and all international flights that depart or arrive in the US. Always contact your airline prior to your flight to confirm any requirements they may have -- such as a copy of your prescription or a letter of medical necessity -- for allowing your device on board.


  • Dimensions:6.48 x 3.30 x 2.02 Inches
  • Weight:10.3 Ounces
  • Materials:Latex Free


  • Dimensions:6.48 x 3.30 x 2.02 Inches
  • Weight:10.4 Ounces
  • Operating Modes:CPAP, Auto-CPAP (APAP)
  • Pressure Range:4 to 20 cm H2O
  • Tubing Compatibility:The Z2 includes a Custom Tube Adapter compatible with all Standard and Performance CPAP Tubing. For proper operation the Tube Adapter MUST ALWAYS be in place when using the Z2 device.
  • Sound Levels:26 dBA
  • Default Settings: 8 CM H2O


  • Comfort Tech:Z-Breathe (Settings = 1 Minimum, 2 Moderate, 3 Maximum)
  • Leak Compensation:Automatic
  • Pressure Ramp:User Adjustable 0 to 45 Minutes
  • Pressure Ramp Start: 4 to CPAP Pressure
  • Altitude Adjustment: Automatic Up To 8000 Feet
  • Supplemental Oxygen: NOT Compatible with Supplemental Oxygen


  • Data Storage: 30 Days of Storage Onboard
  • Data Viewing:Free HDM Data Viewer Software (Windows PC)
  • Data Included: Events and Time of Use


  • Humidifier:Heat Moisture Exchanger (HME) Included for Optional Use
  • Customer service


    I had a few problems with my order. They were beyond helpful.
    Written by , Colorado

  • Great little machine


    That’s it .. nothing more to say
    Written by , Buffalo NY

  • Sent it back


    It was so noisy. I couldn’t sleep so I packed it up and sent it back!
    Written by , North Carolina

  • Exactly as advertised


    Great little machine. Great size. Great customer service (I changed my order a couple of times). Arrived quickly.
    Written by ,